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#4 D-Dimer and its cut-offs for VTE exclusion

Presented by Audrey Carlo and Cécile Hourquet // Special guest François Depasse, Clinical Development Director at Stago

Season 1, episode 4
7 min / Published
By Stago

Welcome to Ask Stago, the Podcast providing expert answers to your expert questions. 
In today’s episode, with François Depasse our Clinical Development Director, we will discuss the selection of a cut-off for D-dimer assay in venous thromboembolism exclusion diagnosis


Sources:  Pernod G, Maignan M, Marlu R. Questioning the use of an age-adjusted D-dimer threshold to exclude venous thromboembolism: analysis of individual patient data from two diagnostic studies: comment. J Thromb Haemost 2016; 14: 2553–4.
Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez, Nils Kucher, Irene Marthe Lang, Mareike Lankeit, Roberto Lorusso, Lucia Mazzolai, Nicolas Meneveau, Fionnuala Ní Áinle, Paolo Prandoni, Piotr Pruszczyk, Marc Righini, Adam Torbicki, Eric Van Belle, José Luis Zamorano, ESC Scientific Document Group, 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC), European Heart Journal, Volume 41, Issue 4, 21 January 2020, Pages 543–603, https://doi.org/10.1093/eurheartj/ehz405.



Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

  • d-dimer
  • cut-off
  • VTE
  • exclusion
  • coagulation
  • hemostasis
  • indications
The show team
Cecile Hourquet
Cecile Hourquet
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