Les mythes en médecine d'urgence - Partie 5

Perrine Truong accueille Nicolas Beysard pour ce 5e épisode des mythes en médecine d'urgence. Les deux mythes discutés ici : l’hydratation intraveineuse permet pas de faire baisser plus rapidement le taux d’alcoolémie des patients ethylisés aigu aux urgences, et le tramadol est un opiacé faible et peu dangereux.

Références du podcast :

Homma Y, Shiga T, Hoshina Y, et al. IV crystalloid fluid for acute alcoholic intoxication prolongs ED length of stay. Am J Emerg Med. 2018 Apr;36(4):673-676.

Terayama T, Sasa R, Nakatani Y, et al. Effect of intravenous fluid therapy for acute alcohol intoxication on length of time from arrival at the emergency department until awakening: A prospective observational cohort study. Acute Med Surg. 2023 May 3;10(1):e841.

Perez SR, Keijzers G, Steele M, Byrnes J, Scuffham PA. Intravenous 0.9% sodium chloride therapy does not reduce length of stay of alcohol-intoxicated patients in the emergency department: a randomised controlled trial. Emerg Med Australas. 2013 Dec;25(6):527-34.

Li J, Mills T, Erato R. Intravenous saline has no effect on blood ethanol clearance. J Emerg Med. 1999 Jan-Feb;17(1):1-5.

Maillard, A., Beysard, N., Mythes en médecine d’urgence : prises en charge intrahospitalières, Rev Med Suisse, 2017/570 (Vol.13), p. 1378–1380.

Etat de lieux de la consommation des antalgiques opioïdes et leurs usage. ANSM, février 2019.

Jeong S, Tchoe HJ, Li J, Shin JY. All-Cause Mortality Associated with Tramadol Use: A Case-Crossover Study. Drug Saf. 2019 Jun;42(6):785-796.

Xie J, Strauss VY, Martinez-Laguna D, et al. Association of Tramadol vs Codeine Prescription Dispensation With Mortality and Other Adverse Clinical Outcomes. JAMA. 2021 Oct 19;326(15):1504-1515.

Zeng C, Dubreuil M, LaRochelle MR, Lu N, Wei J, Choi HK, Lei G, Zhang Y. Association of Tramadol With All-Cause Mortality Among Patients With Osteoarthritis. JAMA. 2019 Mar 12;321(10):969-982.

Stamer UM, Musshoff F, Kobilay M, Madea B, Hoeft A, Stuber F. Concentrations of tramadol and O-desmethyltramadol enantiomers in different CYP2D6 genotypes. Clin Pharmacol Ther. 2007 Jul;82(1):41-7.

Grond S, Sablotzki A. Clinical pharmacology of tramadol. Clin Pharmacokinet. 2004;43(13):879-923.

Roussin A, Soeiro T, Fouque C, et al. Increase of high-risk tramadol use and harmful consequences in France from 2013 to 2018: Evidence from the triangulation of addictovigilance data. Br J Clin Pharmacol. 2022 Aug;88(8):3789-3802.

Hassamal S, Miotto K, Dale W, Danovitch I. Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures. Am J Med. 2018 Nov;131(11):1382.e1-1382.e6.

Thiels CA, Habermann EB, Hooten WM, Jeffery MM. Chronic use of tramadol after acute pain episode: cohort study. BMJ. 2019 May 14;365:l1849.

Nau, J., L’arbre à tramadol existe : il prend racine en Afrique, Rev Med Suisse, 2013/401 (Vol.9), p. 1862–1863.

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A podcast by Perrine Truong

Le podcast incontournable de médecine d'urgence en Suisse romande.

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