S3E12 - Fibrinolysis: the often missed key player of hemostasis
Presented by Audrey Carlo and Cécile Hourquet // Special guest Professor Romaric Lacroix, Professor at the University Hospital La Conception in Marseille in France
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Season 3, episode 12
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Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Professor Romaric Lacroix will explain us how fibrinolysis is important to the whole hemostasis process and how the sample fibrinolytic activity needs to be evaluated and sometimes monitored.
Link to previous podcasts:
-
S1E15 – Disseminated Intravascular Coagulation (DIC) and fibrin related markers
Literature sources:
-
Cointe S, Vallier L, Esnault P, Dacos M, Bonifay A, Macagno N, Harti Souab K, Chareyre C, Judicone C, Frankel D, Robert S, Hraiech S, Alessi MC, Poncelet P, Albanese J, Dignat-George F, Lacroix R. Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock. Blood. 2022 Apr 14;139(15):2377-2391.
-
Cointe S, Harti Souab K, Bouriche T, Vallier L, Bonifay A, Judicone C, Robert S, Armand R, Poncelet P, Albanese J, Dignat-George F et Lacroix R. A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance. J Extracell Vesicles 2018; Jul 16;7(1):1494482
-
Vallier L, Cointe S, Lacroix R, Bonnifay A, Judicone C, Dignat-George F, Hau C.
-
Kwaan. Microparticle and fibrinolysis. Semin Thromb Hemost. 2017 Mar;43(2):129-134
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.
Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation.
In today’s episode, our guest Professor Romaric Lacroix will explain us how fibrinolysis is important to the whole hemostasis process and how the sample fibrinolytic activity needs to be evaluated and sometimes monitored.
Link to previous podcasts:
- S1E15 – Disseminated Intravascular Coagulation (DIC) and fibrin related markers
Literature sources:
- Cointe S, Vallier L, Esnault P, Dacos M, Bonifay A, Macagno N, Harti Souab K, Chareyre C, Judicone C, Frankel D, Robert S, Hraiech S, Alessi MC, Poncelet P, Albanese J, Dignat-George F, Lacroix R. Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock. Blood. 2022 Apr 14;139(15):2377-2391.
- Cointe S, Harti Souab K, Bouriche T, Vallier L, Bonifay A, Judicone C, Robert S, Armand R, Poncelet P, Albanese J, Dignat-George F et Lacroix R. A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance. J Extracell Vesicles 2018; Jul 16;7(1):1494482
- Vallier L, Cointe S, Lacroix R, Bonnifay A, Judicone C, Dignat-George F, Hau C.
- Kwaan. Microparticle and fibrinolysis. Semin Thromb Hemost. 2017 Mar;43(2):129-134
Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.
- fibrinolysis
- plasmin
- microvesicles
- fibrinolytic cross-talk
- ask stago
Previous episode
S3E11 - What is Factor parallelism for?
Presented by Audrey Carlo and Cécile Hourquet // Special guest Tom Childs, Product Manager at Stago
Next episode
S4E1 - Women’s health series (part 1): Women’s health and coagulation
Presented by Audrey Carlo and Lisa Gannon // Special guest Dr Francois Depasse, Clinical Development Director at Stago
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